Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?
Abstract Background Childhood-onset systemic lupus erythematosus (cSLE) is an incurable multi-systemic autoimmune disease.Interferon type I (IFN-I) plays a pivotal role in the pathogenesis of SLE.The objective of this study was to assess the prevalence of the BAKING SODA POWDER IFN-I signature and the contribution of cytosolic nucleic acid receptor